Volume 2 Issue 1
2018-05-18 Research Article
Abstract
Objectives: As the cancer patients are at higher risk of premature deaths due to candidemia. So, the present study aims to evaluate the predictors of candidemia along with its outcomes among hospitalized adults and pediatric cancer patients.
Methods: A retrospective study was conducted at a tertiary care cancer hospital in Lahore, Pakistan. The data was collected from the medical records of all the patients who were found positive for Candida species between 1st January 2017 and 31st June 2017. Data were analyzed by using Statistical Packages for Social Sciences (IBM SPSS Statistics for Windows, Version 21.0. Armonk, NY: IBM Corp.) and Microsoft Excel (MS Office 2010).
Results: Overall, 135 patients were detected with candidemia. Based on blood culture test results, it was found that out of 100 cultures positive for any microorganism there were 2 cases of candidemia. Multivariate analysis revealed that hematological malignancies (AOR: 2.1), and shock (AOR: 9.1) were significantly associated with high risk of mortalities during the index hospitalization, while risk of mortality among cancer patients suffering from Candida albican infection (AOR: 0.47) and those who were administered with antifungal agent after sensitivity report of the fungal culture (AOR: 0.2) was significantly less. Also, there was no significant association of empiric therapy of antifungal agent with the risk of mortality before a positive culture found (p>0.05).
Conclusion: Although, no risk factor was found to be associated significantly with candidemia among cancer patients. But hematological malignancies, non-albican candidemia and shock were predictors of higher risk mortality during index hospitalization.
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001003 Cite this Article
Recent Articles
2021-03-22 Letter to the Editor
Francisco Javier Torres-Gómez*
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001024 Citation
2021-03-17 Review Article
Alejandro Soderini*, Alejandro Aragona, Agustin Quintaie, Horacio Moschen and Martín Mendez
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001023 Citation
2021-03-03 Letter to the Editor
Francisco Javier Torres-Gómez*
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001022 Citation
2020-10-07 Research Article
Teresa Guix, Marco Panichi, Ines Guix, Iván García, Carles Llebaría, Nicolás Achkar, Luis Quinzaños, Hamza Sentisi, Jose Luís Enríquez, Ana Galván, Cristina Pérez-Sánchez, Víctor González, Carmen León and Benjamín Guix*
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001021 Citation
2020-05-25 Case Report
Issam Lalya*, Sana Laatitioui, Ismail Essadi, Abdelhamid El Omrani and Mouna Khouchani
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001020 Citation
2020-04-30 Research Article
Marcos Tobias-Machado*, Ricardo JF de Bragança, Rafael Tourinho-Barbosa Aurus M Dourado and Hamilton C Zampolli
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001019 Citation
2020-04-30 Research Article
Marcos Tobias-Machado*, Edgar O Sarmento, Igor Nunes-Silva and Hamilton C Zampolli
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001018 Citation
2020-04-29 Research Article
Vinicius JA Panico, Lucila H Simardi, Eliney F Faria, Rene Sotelo, Ruben Suarez, Diego Abreu, Andre Meirelles, Edison Schneider, Hamilton C Zampolli and Marcos Tobias-Machado*
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001017 Citation
2020-04-23 Research Article
Tobias Machado* and Anis Taha
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001016 Citation
2020-03-31 Editorial
Muhammed Emin Göktepe, Onur Öztürk* and Mustafa Ünal
Abstract Read Full Article HTMLDOI: 10.29328/journal.acst.1001015 Citation
































