Research Article
Brain and immune system: KURU disease a toxicological process?
Luisetto M*, Behzad Nili-Ahmadabadi, Ghulam Rasool Mashori, Ahmed Yesvi, Ram Kumar Sahu, Heba Nasser, Cabianca luca and Farhan Ahmad Khan
Published: 05/03/2018 | Volume 2 - Issue 1 | Pages: 014-027
Abstract
Starting from observation of pathogenesis of KURU disease we try to investigate the immunologic role played by central nervous systems. A deeply knowledge in the transmission model of this pathology can be an imaging/diagnostic tool to Verify the progression of this prion molecule from gastro intestinal systems to the brain. (After cannibalistic behavior). The prions can be considered a sort of trace ant in KURU to monitoring this process and immune- brain relationship. Interesting information can be obtained useful to produce new pharmacological strategies in some other degenerative brain disease involving innate immune system activation.
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