GUO-JIANG CHEN | Editor
Affilation: Institute of Basic Medical Sciences, P.R.China
I am interested in interaction between inflammation and cancer especially in interplay between gut microbiota, mucosal immune system and gatrointestinal tumors. Specifically, I am very interested in the issues as follows (but not limited): 1. What changes happen to gut microbiota (e.g. composition and metabolites) during the growth and progression of malignancies (e.g. colorectal cancer) and the effects of this alteration on neoplastic transformation; 2. How to affect the growth and progression of gastrointestinal tumors by intestinal mucosal system (e.g. macrophage and ILCs); 3. How to foster immunosuppressive microenvironment caused by intrinsic mutation of oncogenic genes in cancer cells. And I am also interested in cancer immunology (e.g. MDSC generation and differentiation in tumor niche).














