June 2017

Incidence of symptom-driven Coronary Angiographic procedures post-drug-eluting Balloon treatment of Coronary Artery drugeluting stent in-stent Restenosis-does it matter?

Victor Voon*, Dikshaini Gumani, Calvin Craig, Ciara Cahill, Khalid Mustafa, Terry Hennessy, Samer Arnous and Thomas Kiernan

ABSTRACT

Objectives: The clinical impact of drug-eluting balloon (DEB) coronary intervention for drug-eluting in-stent restenosis (DES-ISR) is not fully known. To further evaluate this impact, we aimed to describe the incidence of symptom-driven coronary angiography (...

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Thrombolysis, the only Optimally Rapid Reperfusion Treatment

Victor Gurewich*

ABSTRACT

Thrombolysis with tissue plasminogen activator (tPA) has been plagued by inadequate efficacy and a high risk of intracranial hemorrhage (ICH), which led to its replacement by procedures like percutaneous coronary intervention (PCI) whenever possible. Since this requires hospi...

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Spontaneous rupture of a giant Coronary Artery Aneurysm after acute Myocardial Infarction

Oguzhan Celik, Mucahit Yetim, Tolga Dogan, Lutfu Bekar, Macit Kalcık* and Yusuf Karavelioglu

CASE PRESENTATION

Coronary artery aneurysm is commonly defined as a localized dilatation exceeding the diameter of adjacent normal coronary segments by 50% [1]. Coronary artery aneurysms may be fusiform, involving the full circumference of the coronary artery, or saccular, involving o...

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CRISPR genome editing: A general view

Ram Mohan Ram Kumar*

Editorial

CRISPR technology has presented a path forward for genomic engineering and gene modification. The framework for the use of CRISPR technology to manipulate the human genome is of great interest and the form of its development and application has excited the researchers and bi...

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Mitomycin-C Use and Complications in Ophthalmology

Tongabay Cumurcu*

INTRODUCTION

Mitomycin-C, First found its way into ophthalmic use in 1969, in Japan, where recurrent pterygia were successfully treated with the drug which is an antineoplastic / antibiotic agent isolated from the soil bacterium Streptomyces caespitosus [1]. It is an anti-metabol...

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The interaction between photonic technology and physical exercise: The action of low-level laser therapy

Antonio Eduardo de Aquino Jr* and Fernanda Mansano Carbinatto

ABSTRACT

Introduction: Obesity is a global-level epidemic. Together with this disease, called chronic subclinical inflammatory disease, many other diseases, known as comorbidities, arise.

Objective: To show that the association between low-l...

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The impact of geographical origin on specific properties of pine honey

Ioannis K. Karabagias*, Christos Nikolaou and Ilias Gatzias

Abstract

Pine honey represents the major type of honey produced in Greece. In that sense, the aim of the present study was to investigate if specific physicochemical and bioactive properties could serve as markers of its geographical origin. For this purpose, forty pine honey samples ...

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Endovascular treatment of complex cerebral arterial saccular aneurysms with different methods of coiling: 14 years of experience review

Dmytro V Scheglov*, Stanislav V Konotopchik, Maryna Y Mamonova and Oleg E Sviridyuk

ABSTRACT

The Objective: to improve the treatment results for patients with cerebral arterial saccular aneurysms by optimizing of differentiated approach to the using of endovascular assisting occlusion techniques.

Materials and Methods: The ...

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Clinical significance of Urinary Amylase in Acute Pancreatitis

Mumtaz Din Wani, Mushtaq Chalkoo*, Zaheer Ahmed, Awhad Mueed Yousuf, Yassar Arafat, Syed Shakeeb Arsalan and Jaffar Hussain

Abstract

Acute pancreatitis forms a major bulk of our inpatient admission due to gall stone disease. Diagnosis of acute pancreatitis remains a challenge even now. Serum amylase remains the most commonly used biochemical marker for its diagnosis but its sensitivity can be reduced by la...

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Function Prediction of Proteins from their Sequences with BAR 3.0

Giuseppe Profiti, Pier Luigi Martelli and Rita Casadio*

SUMMARY

Protein functional annotation requires time and effort, while sequencing technologies are fast and cheap. For this reason, the development of software tools aimed at predicting protein function from sequences can help in protein annotation.
In this paper, we describe ho...

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Chemotherapy Exposure and outcomes of Chronic Lymphoid Leukemia Patients

Josephina G Kuiper*, Patience Musingarimi, Christoph Tapprich, Fernie JA Penning-van Beest and Maren Gaudig

ABSTRACT

This study describes chemotherapy exposure, healthcare utilization, overall survival (OS) and progression-free survival (PFS) among patients diagnosed with chronic lymphoid leukemia (CLL). Newly diagnosed CLL patients who received chemotherapy were selected from the Eindhoven...

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Time to Terminate LNT: Radiation Regulators Should Adopt LT

Jeffry A Siegel*, Bill Sacks and James S Welsh

ABSTRACT

The linear no-threshold hypothesis (LNT)-the basis of radiation regulatory policy-extrapolates from observed high-dose harm to assumed low-dose harm, entailing that all ionizing radiation is harmful, by denying any biological response to damage and asserting cumulative lifeti...

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Reliability and validity of the Sit-To-Stand Test to assess Global Foot Mobility

Mark W Cornwall*, Carissa Lane, Jennifer Norwood, Sara Patterson and Daniel Strauss

Summary

The Sit-to-Stand test (STST) involves comparing the change in a person’s non-weight-bearing and weight-bearing foot posture to quickly classify a person’s overall foot mobility. Despite the simplicity of the test, its reliability and validity has not been establish...

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Successful Therapy with intravenous gamma globulin in two children with postinfectious bronchiolitis obliterans

Sevgi Pekcan , Bahar Gökturk* and Ismail Reisli

Case Report

Bronchiolitis obliterans (BO) is an infrequent clinical syndrome characterized by the chronic obstruction of small airways due to fibrosis [1]. Intravenous immunoglobulin (IVIG) could be used for treatment while underlying immune mechanisms in the pathogenesis of BO exist ...

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Acute and chronic changes in massive Barium Sulfate aspiration in an infant who subsequently was diagnosed with severe Gastro-esophageal Reflux

Sevgi Pekcan*

ABSTRACT

The barium is often used in radiocontrast examinations of the digestive system because of mucosal absorption is limited. Massive barium aspiration is a rare complication, especially when there is no anatomic or neurological deficit. The depending on barium concentration can c...

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Direct Carotid Puncture for Flow Diverter Stent Insertion

Bhogal P*, Phillips TJ and Makalanda HLD

ABSTRACT

Objective: To report our experience of direct carotid puncture and its use in the management of a large and rapidly expanding cavernous aneurysm.

Methods: A patient with a cavernous aneurysm that measured 25mm in maximum diameter un...

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Natural and effective ways of purifying lake water

Swapnil Lokhande and Savita Dixit*

Abstract

Water resources play an integral part in the life of a living being. The various water resources that are present on the earth’s surface are in the form of oceans, seas, lakes, rivers, ponds, waterfalls etc. Among these water resources Lakes and reservoirs are vital for...

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Hydraulic jump experiment in a rectangular open channel flume

Mostafa M El-Seddik*

Abstract

This paper presents a laboratory experiment for the formation of hydraulic jump in a rectangular open channel flume to accurately explore the effect of flow structures on water resources. This experiment illustrates the behavior of super-critical flow under sluice gate for va...

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Esthetic recovery of permanent Mandibular Lateral Incisor using biological post after non-surgical healing of Periradicular Lesion: A Case Report

Amit Kumar Garg, Neha Agrawal* and Rajendra Kumar Tewari and Surendra Kumar Mishra

ABSTRACT

Statement of the problem: Anterior tooth fracture, as a result of traumatic injuries, frequently occurs in dentistry. This leads to necrosis of pulp and periapical pathology. The goal of endodontic and restorative dentistry is to retain natural teeth with max...

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Efficacy of early Hyperbaric Oxygen Therapy in Central Retinal Artery Occlusion

Ayse Gul Kocak Altintas* and Mehmet Citirik

Abstract

A 60-year-old woman had central retinal artery occlusion (CRAO) presented to the ophthalmology department with a sudden, painless loss of vision. Her initial visual acuity was light perception and she treated with hyperbaric oxygen therapy (HBOT) 4 hours after the development...

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Concise Review: Considerations for the Formulation, Delivery and Administration Routes of Biopharmaceuticals

Amir Mohammed Alsharabasy*

Abstract

The drugs of biological origins have attracted the attention of many pharmaceutical companies where it is essential to protect the heterogeneous nature and the optimal three dimensional structures of the different macromolecules. These molecules are used in both the investiga...

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A possible Etiology and new treatment of Burning Mouth Syndrome and allied condition

Sudhakar Pattanaik*

ABSTACT

Introduction: Burning mouth syndrome, oral sub mucous fibrosis, leukoplakia, etc are the different manifestations of a common disease as per the surmise of various authors. There is no known cause and no specific treatment. Attempt is made in this study to fin...

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MicroRNA Therapeutics in Triple Negative Breast Cancer

Sarmistha Mitra*

ABSTRACT

Breast cancer is a complex disease and one of the main causes of cancer-related mortality in women worldwide. In case of approximately 15% of all breast cancers, three markers i.e. estrogen receptors (ER), progesterone receptors (PR) and human epidermal growth factor receptor...

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Acute Tubulointerstitial Nephritis due to Phenytoin: Case Report

Nilzete Liberato Bresolin*, Pedro Docusse Junior, Maria Beatriz Cacese Shiozawa, Marina Ratier de Brito Moreira and Natalia Galbiatti Silveira

SUMMARY

Introduction: Acute tubulointerstitial nephritis (ATIN) is an acute kidney injury (AKI) resulting from damage to the tubulointerstitial tissue due to infection, trauma, or use of medication. It is clinically non-specific.

Case: A tee...

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Recurrent Mucoepidermoid Carcinoma of Parotid with Facial Tics - Report of an unusual case

Pirabu Sakthivel*, Chirom Amit Singh, Smriti Panda, Suresh Chandra Sharma, Konki Malla Abhilash and Milind Sagar

ABSTRACT

We report an interesting case of a 21 year old male who presented with recurrent mucoepidermoid carcinoma of parotid with facial nerve involvement as facial tics. Intraoperatively, the tumour was noted to be firm, irregular and adherent to the underlying structures. The patie...

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Wild-type Agrobacterium rhizogenesmediated gene transfer in plants: Agrobacterium virulence and selection of transformants

Mohammad M Rana, Muhammad Abdullah, Ferdinand L Shamalla and Shu Wei*

ABSTRACT

Agrobacterium rhizogenesATCC 15834 wild type strain was transformed with the binary vector pBI121 using the heat shock method. The transformed Agrobacterium was then tested for virulence through tobacco leaf explant transformation. Compared to the non-t...

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Hypernatremia and central Diabetes Insipidus following Neurosurgical procedure of Trauma

Awad Magbri*, Eussera El-Magbri and Seth Hershit

INTRODUCTION

The greater risk of hypernatremia in patients over 65 years old are associated with impaired mental status and physical disability which may result in impaired sensation to thirst, impaired ability to express thirst, and/or decrease access to water [1,2]. Normally, anti-d...

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The Neuromuscular diseases in Pediatric Dental Office

Ambarkova Vesna*

Abstract

The neuromuscular disorders may be hereditary, autoimmune, and in some cases with unknown etiology. These diseases are characterized by progressive course, muscle weakness, and in an advanced stage with binding the patient to a wheelchair. This group includes a number of dise...

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Fungi present in home and their impact on human health-A short review

Mariusz Dylag*

ABSTRACT

It is estimated that even up to 30% of buildings worldwide may be the subject of complaints connected with the quality of indoor air. Potential sources of air pollution can be both organic and inorganic particles. This article focuses on biological air pollutants from living ...

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Protective functions of AEURA in Cell Based Model of Stroke and Alzheimer disease

Jigar Modi Ahmed Altamimi, Ashleigh Morrell, Hongyuan Chou, Janet Menzie, Andrew Weiss, Michael L Marshall, Andrew Li, Howard Prentice* and Jang-Yen Wu*

ABSTRACT

Stroke and neurodegenerative diseases including Alzheimer’s disease (AD) are responsible for a major proportion of mortalities in the elderly. We have previously investigated novel mechanism-based therapies of AEURA in cell culture models against viral infection and in ...

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Comparison of Vitreous Protein Profiles of Rabbits subjected to Acute Carbon Monoxide poisoning and normal animal after death

Agoro ES*, Akubugwo EI, Chinyere GC and Samuel R

ABSTRACT

Acute carbon monoxide (CO) poisoning is caused by the inhalation of large quantity of CO within short time leading to morbidity and mortality. In this study, a total of eighteen (18) rabbits were divided into three (3) groups of six (6) animals each. The first group first gro...

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Antagonistic features displayed by Plant Growth Promoting Rhizobacteria (PGPR): A Review

Mohsin Tariq*, Muhammad Noman, Temoor Ahmed, Amir Hameed, Natasha Manzoor and Marriam Zafar

ABSTRACT

Soil dwelling bacteria able to colonize plant roots and closely associated soil are referred to as rhizobacteria. A wide range of rhizobacteria has the ability to promote plant growth directly by producing phytohormone and nutrients; and indirectly by controlling plant pathog...

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